You can do more with the tabs in EditPad, beyond activating a file by clicking on its tab.
To quickly close a tab, move the mouse pointer over it and push down the wheel button on your mouse. If the file didn't have any unsaved changes, EditPad will close it instantly, without even activating it.
You can access other common file-related commands such as File|Save and File|Close All but Current quickly by clicking on one of the tabs with the right hand button of your mouse. If the tab you right-clicked on isn't the active tab, EditPad will activate the file first. If a command you often use isn't available in the right-click menu, you can add it by customizing the toolbars and menus.
Right-clicking a file tab also shows a few special commands such as the Read Only command for toggling the file's read-only status, and Copy Path to Clipboard for placing the file's full path onto the clipboard.
To quickly start with a blank, untitled file, double-click on the empty space after the last tab. Other common commands for opening files and commands affecting all files are available in the context menu that appears when you right-click on the empty space after the last tab. This menu is also configurable.
Right-clicking on a project tab shows a context menu with various commands to manage the project. You can configure this menu.
To quickly start with an empty project, double-click the empty space after the last project tab. This empty space too has a configurable context menu. It shows commands for opening projects and commands affecting all projects.